The STM32F407VET6 microcontroller, part of the STM32F4 series, is widely used for a variety of embedded system applications, offering powerful processing capabilities and an array of peripherals for developers to tap into. However, to truly unlock the full potential of this microcontroller, engineers must focus on optimizing both its performance and efficiency. Here, we discuss some best practices that engineers can implement to make the most of the STM32F407VET6 in their designs.